Leicester have looked a completely different side under Brendan Rodgers as they have been playing much closer to their potential. Chelsea will likely relax a little here after Thursday night's game and that could hand a motivated Leicester the opportunity to win the final home game for their fans.
There is nothing riding on this match for either team which makes it an unpredictable one. Burnley will want to end the season on a high but they have a poor record against Arsenal who have won the last nine meetings between the two so that may offer a guide as to how this may play out.
City's relentless run to title glory continues and if they can produce their 14th consecutive win here, that will seal it for Guardiola's men. Brighton will be no pushovers and will make it hard for City to break them down, but one would fully expect City to eventually find a way past them.
Liverpool come into this final match of the season knowing the title is out of their hands, but they simply have to win. Wolves present a difficult opponent for them as they are in fine form, and while Liverpool have to be favoured, do not rule out Wolves causing them more than a few alarms.
Spurs will be riding high after Wednesday's miraculous comeback against Ajax but Mauricio Pochettino may decide to rest a number of his regular starters here. Everton are finishing with a flourish and they are more than capable of travelling to London and returning with at least a point from this.
Neither of these two teams have had much to shout about in these final weeks of the season but United especially will be desperate to give their fans something to cheer in this final game. This is unlikely to be a goalfest but United should have enough to edge it and may even keep a clean sheet.
Crystal Palace are ending the season in relatively good form as they are enjoying the fact they can play with freedom without the threat of relegation. Bournemouth continue to have a whole raft of injuries and Roy Hodgson's men should be able to take advantage of that.
Fulham have shown great desire in these final weeks to pick up three wins in their last four despite being relegated weeks ago. They will want to give their fans something to cheer, but this has all the hallmarks of a low-scoring and relatively uninspiring match between these two sides.
Southampton's season is fading badly and the 3-0 loss at West Ham last week will be a result Ralph Hasenhuttl will be desperate to avenge. They face Huddersfield who picked up a draw last week but are woeful on their travels, and the hosts should claim all three points in this season finale.
Watford's form has dropped off a little since they won the FA Cup semi-final against Wolves, but they could do with a win to go into the final against Man City with some belief. West Ham have won their last two matches, but a focused Watford side should be motivated enough to win this match.
Arsenal cannot rely on solely on winning the Europa League to qualify for the Champions League so they need to get back to winning ways here. Brighton will look to deny them time and space, but the visitors do not possess the firepower to concern the Gunners who should pick up all three points.
Chelsea are competing well in both the Premier League and Europa League at the moment and there is no margin for error now. Their home form in the league has been good with five wins and two draws in their last seven and they can continue that run in a match which should contain goals.
This will be another tough test for Man City as Leicester are no pushovers and are ending the season in fine form. That said, Guardiola's men have had a free midweek and they will have overcome any fatigue that they were suffering so expect their relentless pursuit of the title to continue here.
Man Utd simply have to win if they are to have any chance of reaching the top four, and Solskjaer will be desperate for a response from his players. Their form has been poor of late but they will likely go all out on the attack here and that could lead to a lively game which they should win.