Lionel Messi is now on 57 hat-tricks and counting in his career:
| # | DATE | OPPONENT | COMPETITION | RESULT | OUTCOME | GOALS |
| 1 | 10/03/2007 | Real Madrid | La Liga | 3-3 | Draw | 3 |
| 2 | 06/01/2009 | Atletico Madrid | Copa del Rey | 3-1 | Win | 3 |
| 3 | 10/01/2010 | Tenerife | La Liga | 5-0 | Win | 3 |
| 4 | 14/03/2010 | Valencia | La Liga | 3-0 | Win | 3 |
| 5 | 21/03/2010 | Real Zaragoza | La Liga | 4-2 | Win | 3 |
| 6 | 06/04/2010 | Arsenal | Champions League | 4-1 | Win | 4 |
| 7 | 21/08/2010 | Sevilla | Spanish Super Cup | 4-0 | Win | 3 |
| 8 | 20/11/2010 | Almeria | La Liga | 8-0 | Win | 3 |
| 9 | 12/01/2011 | Real Betis | Copa del Rey | 5-0 | Win | 3 |
| 10 | 05/02/2011 | Atletico Madrid | La Liga | 3-0 | Win | 3 |
| 11 | 17/09/2011 | Osasuna | La Liga | 8-0 | Win | 3 |
| 12 | 24/09/2011 | Atletico Madrid | La Liga | 5-0 | Win | 3 |
| 13 | 29/10/2011 | Mallorca | La Liga | 5-0 | Win | 3 |
| 14 | 01/11/2011 | Viktoria Plzen | Champions League | 4-0 | Win | 3 |
| 15 | 22/01/2012 | Malaga | La Liga | 4-1 | Win | 3 |
| 16 | 19/02/2012 | Valencia | La Liga | 5-1 | Win | 4 |
| 17 | 29/02/2012 | Switzerland | Friendly International | 3-1 | Win | 3 |
| 18 | 07/03/2012 | Bayer Leverkusen | Champions League | 7-1 | Win | 5 |
| 19 | 20/03/2012 | Granada | La Liga | 5-3 | Win | 3 |
| 20 | 02/05/2012 | Malaga | La Liga | 4-1 | Win | 3 |
| 21 | 05/05/2012 | Espanyol | La Liga | 4-0 | Win | 4 |
| 22 | 09/06/2012 | Brazil | Friendly International | 4-3 | Win | 3 |
| 23 | 20/10/2012 | Deportivo La Coruna | La Liga | 5-4 | Win | 3 |
| 24 | 27/01/2013 | Osasuna | La Liga | 5-1 | Win | 4 |
| 25 | 15/06/2013 | Guatemala | Friendly International | 4-0 | Win | 3 |
| 26 | 01/09/2013 | Valencia | La Liga | 3-2 | Win | 3 |
| 27 | 18/09/2013 | Ajax | Champions League | 4-0 | Win | 3 |
| 28 | 16/03/2014 | Osasuna | La Liga | 7-0 | Win | 3 |
| 29 | 23/03/2014 | Real Madrid | La Liga | 4-3 | Win | 3 |
| 30 | 22/11/2014 | Sevilla | La Liga | 5-1 | Win | 3 |
| 31 | 25/11/2014 | APOEL | Champions League | 4-0 | Win | 3 |
| 32 | 07/12/2014 | Espanyol | La Liga | 5-1 | Win | 3 |
| 33 | 18/01/2015 | Deportivo La Coruna | La Liga | 4-0 | Win | 3 |
| 34 | 15/02/2015 | Levante | La Liga | 5-0 | Win | 3 |
| 35 | 08/03/2015 | Rayo Vallecano | La Liga | 6-1 | Win | 3 |
| 36 | 09/01/2016 | Granada | La Liga | 4-0 | Win | 3 |
| 37 | 03/02/2016 | Valencia | Copa del Rey | 7-0 | Win | 3 |
| 38 | 03/03/2016 | Rayo Vallecano | La Liga | 5-1 | Win | 3 |
| 39 | 11/06/2016 | Panama | Copa America | 5-0 | Win | 3 |
| 40 | 13/09/2016 | Celtic | Champions League | 7-0 | Win | 3 |
| 41 | 19/10/2016 | Manchester City | Champions League | 4-0 | Win | 3 |
| 42 | 09/09/2017 | Espanyol | La Liga | 5-0 | Win | 3 |
| 43 | 19/09/2017 | Eibar | La Liga | 6-1 | Win | 4 |
| 44 | 11/10/2017 | Ecuador | World Cup Qualifiers | 3-1 | Win | 3 |
| 45 | 07/04/2018 | Leganes | La Liga | 3-1 | Win | 3 |
| 46 | 29/04/2018 | Deportivo La Coruna | La Liga | 4-2 | Win | 3 |
| 47 | 30/05/2018 | Haiti | Friendly International | 4-0 | Win | 3 |
| 48 | 18/09/2018 | PSV | Champions League | 4-0 | Win | 3 |
| 49 | 16/12/2018 | Levante | La Liga | 5-0 | Win | 3 |
| 50 | 23/02/2019 | Sevilla | La Liga | 4-2 | Win | 3 |
| 51 | 17/03/2019 | Real Betis | La Liga | 4-1 | Win | 3 |
| 52 | 09/11/2019 | Celta Vigo | La Liga | 4-1 | Win | 3 |
| 53 | 07/12/2019 | Mallorca | La Liga | 5-2 | Win | 3 |
| 54 | 22/02/2020 | Eibar | La Liga | 5-0 | Win | 4 |
| 55 | 10/09/2021 | Bolivia | World Cup Qualifiers | 3-0 | Win | 3 |
| 56 | 05/06/2022 | Estonia | Friendly International | 5-0 | Win | 5 |
| 57 | 29/03/2023 | Curacao | Friendly International | 7-0 | Win | 3 |