Millman created a huge upset when he beat Federer in four sets at the 2018 US Open in the Round of 16. Federer has formidable success at the Halle Open with nine titles to his name and given that Millman has performed poorly this season, expect the Swiss world number three to dispatch the Australian easily in two sets.
The winner between Tsonga and Paire will most likely face the prospect of facing Roger Federer in the second round. Tsonga leads the head-to-head against his fellow Frenchman, but Paire won the most recent match in Marrakech this year and expect the younger Paire to beat the veteran Tsonga who is overcoming recent injury and a lack of form.
Del Potro and Shapovalov have both won a game apiece against one another and the Argentine won the last meeting in Auckland on a hard court. Shapovalov encountered a poor clay season and without much success on grass, expect the more experienced Del Potro to advance to the next round at Queen’s Club.
Kyle Edmund will have home support as he faces a tough challenge against the top-ranked Stefanos Tsitsipas at Queen’s Club. This will be the first meeting between the pair and Edmund has struggled with a knee injury recently so expect the Greek world number six to beat the Britain in the first round at Queen’s.
Barring injury or any other disaster, the defending US Open champion and runaway world number one will be the man to beat once again.
The scene is set at Roland-Garros for Rafa Nadal to win his 12th French Open with Dominic Thiem standing in the way as he attempts to put a dent in Nadal’s love story on the Parisian clay.
Marketa Vondrousova’s win over British number one Johanna Konta was an almost instant revenge for her exit in Rome last month to Konta in the round of 16, where the Czech had displayed her credentials with a third-round win over Simona Halep.
Nobody would have predicted that 17-year-old Amanda Anisimova would reach the semi-finalsstage of Roland-Garros but she has proved doubters wrong with a game that looks so assured for such a young player.
At 19 years old, Marketa Vondrousova has already troubled the top-end of the women’s game and will be rocketing up the rankings table no matter the result here.
It seems as much a terrible shame that this match is not the 2019 Roland-Garros final as it is to attempt to predict it. There is no question that Rafael Nadal, world number two, is the favourite on clay anyway, let alone at the Grand Slam he has seen fit to dominate throughout his career.
Both of these players have had strong routes to the final eight, with Amanda Anisimova especially impressive in her efforts, having not dropped a set in four matches but she comes up against tournament favourite Simona Halep here.
Novak Djokovic will finally have a challenge on his hands in the form of young pretender-to-the-throne Alexander Zverev who is level with the Serb on two wins apiece. The German has had a far more difficult time of it coming into this quarter-final clash but this could also be a positive for a 22-year-old with fitness in abundance.
This is perhaps the hardest quarter-final to choose on the men’s side of the draw between two excellent, exciting young (ish) players. With Novak Djokovic or Sascha Zverev awaiting the victor in the semi-final, this is a massive opportunity for either Dominic Thiem or Karen Khachanov to take.
Given his remarkable record in deciding sets, Nishikori's best chance of success here appears to be taking Nadal to a fifth set but that is far easier said than done against the greatest clay-court player of all time.