Yet more change for the Bills in the summer with Head Coach Sean McDermott and GM Brandon Beane coming into the team from Carolina.
The team offloaded their injury-prone star WR Sammy Watkins in a trade with the Rams but added Eagles WR Jordan Matthews to their ranks.
With the spotlight on whether QB Tyrod Taylor can be a major contributor, they will rely on rusher LeSean McCoy to make a major impact.
NEW YORK JETS
The Jets are the team everybody is picking to bomb this season so expectations are extremely low.
The departure of Sheldon Richardson last week to the Seahawks was another ominous warning that this could be a long season for them.
Todd Bowles has chosen Josh McCown as starting QB but none of their options are convincing and Hackenberg will challenge him at some point.
Analysis - what to expect Neither team inspire much coming into the new season but the Bills have far more to be optimistic about than the Jets who have stripped themselves of all their major assets. Both will want to get their running games going to eat up the clock and establish control so expect a low-scoring game.