Third-seed Cilic eased into the second round following a straights sets win over James Duckworth in a rain-interrupted match on Tuesday.
The big-serving Croat is clearly feeling in confident mood as he has already admitted to thinking about a potential semi-final showdown with reigning champion Rafael Nadal.
Such a run would constitute his best performance at the French Open but he must first navigate this second round match against a player who will be an unknown quantity to him.
Hurkacz made it through three qualifying rounds to feature in his first ever Grand Slam main draw and he then went on to upset Tennys Sandgren in the first round, prevailing in four sets.
The 21-year-old Pole has yet to turn pro and given that he has already exceeded expectations, he should be able to play with freedom against the 2014 US Open champion.
The world number 188 plays mainly on the Challenger Tour so this second round encounter on the main court at Roland-Garros is certainly uncharted territory for him.
Cilic is unlikely to know a great deal about Hurkacz given that his opponent is playing in his first Grand Slam event but the world number four has enough experience to avoid complacency. Cilic looked assured in his first round win over James Duckworth despite testing conditions and appears in good shape to record back-to-back straight sets wins on Philippe Chatrier.